Bioinformatic analysis of bacteria and host cell dual RNA-sequencing experiments
نویسندگان
چکیده
منابع مشابه
A Laboratory Methodology for Dual RNA-Sequencing of Bacteria and their Host Cells In Vitro
Dual RNA-Sequencing leverages established next-generation sequencing (NGS)-enabled RNA-Seq approaches to measure genome-wide transcriptional changes of both an infecting bacteria and host cells. By simultaneously investigating both organisms from the same biological sample, dual RNA-Seq can provide unique insight into bacterial infection processes and reciprocal host responses at once. However,...
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Deep RNA sequencing was used to simultaneously analyze vaccinia virus (VACV) and HeLa cell transcriptomes at progressive times following infection. VACV, the prototypic member of the poxvirus family, replicates in the cytoplasm and contains a double-stranded DNA genome with approximately 200 closely spaced open reading frames (ORFs). The acquisition of a total of nearly 500 million short cDNA s...
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ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2017
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/bbx043